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Substance abuse

MedGen UID:
152849
•Concept ID:
C0740858
•
Mental or Behavioral Dysfunction
Synonyms: Abuse, Substance; Substance Abuse; Substance Abuses
SNOMED CT: Substance abuse (66214007); Harmful substance use (66214007)
 
Monarch Initiative: MONDO:0002491

Definition

Maladaptive pattern of drug or alcohol use that may lead to social, occupational, psychological, or physical problems. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSubstance abuse

Professional guidelines

PubMed

Comprehensive, Evidence-Based, Consensus Guidelines for Prescription of Opioids for Chronic Non-Cancer Pain from the American Society of Interventional Pain Physicians (ASIPP).
Manchikanti L, Kaye AM, Knezevic NN, Giordano J, Applewhite MK, Bautista A, Soin A, Blank SK, Sanapati MR, Karri J, Christo PJ, Abd-Elsayed A, Kaye AD, Calodney A, Navani A, Gharibo CG, Harned M, Gupta M, Broachwala M, Sehgal N, Kaufman A, Wargo B, Solanki DR, Hsu ES, Limerick G, Dennis A, Swicegood JR, Slavin K, Snook L, Pasupuleti R, Kosanovic R, Justiz R, Barkin R, Atluri S, Shah S, Pampati V, Helm Ii S, Grami V, Myckowiak V, Galan V, Singh V, Manocha V, Hirsch JA
Pain Physician 2023 Dec;26(7S):S7-S126. PMID: 38117465
Borderline Personality Disorder: Clinical Guidelines for Treatment.
Stone MH
Psychodyn Psychiatry 2022 Spring;50(1):45-63. doi: 10.1521/pdps.2022.50.1.45. PMID: 35235397
Consensus Guidelines for Therapeutic Drug Monitoring in Neuropsychopharmacology: Update 2017.
Hiemke C, Bergemann N, Clement HW, Conca A, Deckert J, Domschke K, Eckermann G, Egberts K, Gerlach M, Greiner C, Gründer G, Haen E, Havemann-Reinecke U, Hefner G, Helmer R, Janssen G, Jaquenoud E, Laux G, Messer T, Mössner R, Müller MJ, Paulzen M, Pfuhlmann B, Riederer P, Saria A, Schoppek B, Schoretsanitis G, Schwarz M, Gracia MS, Stegmann B, Steimer W, Stingl JC, Uhr M, Ulrich S, Unterecker S, Waschgler R, Zernig G, Zurek G, Baumann P
Pharmacopsychiatry 2018 Jan;51(1-02):9-62. Epub 2017 Sep 14 doi: 10.1055/s-0043-116492. PMID: 28910830

Curated

UK NICE Clinical Guideline CG192, Antenatal and postnatal mental health: clinical management and service guidance, 2020

Recent clinical studies

Etiology

Adolescent Substance Abuse.
Garofoli M
Prim Care 2020 Jun;47(2):383-394. Epub 2020 Feb 21 doi: 10.1016/j.pop.2020.02.013. PMID: 32423721
Substance Abuse Prevention, Assessment, and Treatment for Lesbian, Gay, Bisexual, and Transgender Youth.
Aromin RA Jr
Pediatr Clin North Am 2016 Dec;63(6):1057-1077. Epub 2016 Oct 12 doi: 10.1016/j.pcl.2016.07.007. PMID: 27865333
Substance Use and Substance Abuse--What's in a Name?
Savage CL
J Addict Nurs 2016 Jan-Mar;27(1):47-50. doi: 10.1097/JAN.0000000000000111. PMID: 26950842
Adolescent substance abuse and suicide.
Rowan AB
Depress Anxiety 2001;14(3):186-91. doi: 10.1002/da.1065. PMID: 11747129
Opiate treatments.
Johns A
Addiction 1994 Nov;89(11):1551-8. doi: 10.1111/j.1360-0443.1994.tb03757.x. PMID: 7841870

Diagnosis

Serratia marcescens Endocarditis.
Oliver T, Vazquez J
J Investig Med High Impact Case Rep 2023 Jan-Dec;11:23247096231222414. doi: 10.1177/23247096231222414. PMID: 38146713Free PMC Article
Adolescent Substance Abuse.
Garofoli M
Prim Care 2020 Jun;47(2):383-394. Epub 2020 Feb 21 doi: 10.1016/j.pop.2020.02.013. PMID: 32423721
Supervised injection services: what has been demonstrated? A systematic literature review.
Potier C, Laprévote V, Dubois-Arber F, Cottencin O, Rolland B
Drug Alcohol Depend 2014 Dec 1;145:48-68. Epub 2014 Oct 23 doi: 10.1016/j.drugalcdep.2014.10.012. PMID: 25456324
Infective endocarditis.
Starakis I
Infect Disord Drug Targets 2010 Feb;10(1):21. doi: 10.2174/187152610790410864. PMID: 20218948
Developing a plan of care using the Roper, Logan and Tierney model.
Mooney M, O'Brien F
Br J Nurs 2006 Sep 14-27;15(16):887-92. doi: 10.12968/bjon.2006.15.16.21854. PMID: 17108861

Therapy

Efficacy and Safety of Ketamine vs Electroconvulsive Therapy Among Patients With Major Depressive Episode: A Systematic Review and Meta-analysis.
Rhee TG, Shim SR, Forester BP, Nierenberg AA, McIntyre RS, Papakostas GI, Krystal JH, Sanacora G, Wilkinson ST
JAMA Psychiatry 2022 Dec 1;79(12):1162-1172. doi: 10.1001/jamapsychiatry.2022.3352. PMID: 36260324Free PMC Article
Lithium treatment of Bipolar disorder in adults: A systematic review of randomized trials and meta-analyses.
Fountoulakis KN, Tohen M, Zarate CA Jr
Eur Neuropsychopharmacol 2022 Jan;54:100-115. doi: 10.1016/j.euroneuro.2021.10.003. PMID: 34980362Free PMC Article
The Role of New Technologies to Prevent Suicide in Adolescence: A Systematic Review of the Literature.
Forte A, Sarli G, Polidori L, Lester D, Pompili M
Medicina (Kaunas) 2021 Jan 26;57(2) doi: 10.3390/medicina57020109. PMID: 33530342Free PMC Article
Methamphetamine-Related Disorders.
Gouzoulis-Mayfrank E, Härtel-Petri R, Hamdorf W, Havemann-Reinecke U, Mühlig S, Wodarz N
Dtsch Arztebl Int 2017 Jun 30;114(26):455-461. doi: 10.3238/arztebl.2017.0455. PMID: 28705298Free PMC Article
Prevention, early intervention, harm reduction, and treatment of substance use in young people.
Stockings E, Hall WD, Lynskey M, Morley KI, Reavley N, Strang J, Patton G, Degenhardt L
Lancet Psychiatry 2016 Mar;3(3):280-96. Epub 2016 Feb 18 doi: 10.1016/S2215-0366(16)00002-X. PMID: 26905481

Prognosis

A comprehensive nationwide study of the incidence rate and lifetime risk for treated mental disorders.
Pedersen CB, Mors O, Bertelsen A, Waltoft BL, Agerbo E, McGrath JJ, Mortensen PB, Eaton WW
JAMA Psychiatry 2014 May;71(5):573-81. doi: 10.1001/jamapsychiatry.2014.16. PMID: 24806211
Association of alcohol consumption with selected cardiovascular disease outcomes: a systematic review and meta-analysis.
Ronksley PE, Brien SE, Turner BJ, Mukamal KJ, Ghali WA
BMJ 2011 Feb 22;342:d671. doi: 10.1136/bmj.d671. PMID: 21343207Free PMC Article
Not mission impossible.
Parsons J
Aust Fam Physician 2009 Mar;38(3):85. PMID: 19283243
Impaired healthcare professional.
Baldisseri MR
Crit Care Med 2007 Feb;35(2 Suppl):S106-16. doi: 10.1097/01.CCM.0000252918.87746.96. PMID: 17242598
Prevalence and development of psychiatric disorders in childhood and adolescence.
Costello EJ, Mustillo S, Erkanli A, Keeler G, Angold A
Arch Gen Psychiatry 2003 Aug;60(8):837-44. doi: 10.1001/archpsyc.60.8.837. PMID: 12912767

Clinical prediction guides

Algorithms to Identify Nonmedical Opioid Use.
Brondeel KC, Malone KT, Ditmars FR, Vories BA, Ahmadzadeh S, Tirumala S, Fox CJ, Shekoohi S, Cornett EM, Kaye AD
Curr Pain Headache Rep 2023 May;27(5):81-88. Epub 2023 Apr 6 doi: 10.1007/s11916-023-01104-7. PMID: 37022564
Optimizing SAR-PAGE.
Reihlen P, Blobel M, Kempkes R, Reichel C, Völker Schänzer E, Majer B, Schänzer W
Drug Test Anal 2015 Nov-Dec;7(11-12):1014-6. Epub 2015 Nov 26 doi: 10.1002/dta.1915. PMID: 26607413
Urine drug screening: practical guide for clinicians.
Moeller KE, Lee KC, Kissack JC
Mayo Clin Proc 2008 Jan;83(1):66-76. doi: 10.4065/83.1.66. PMID: 18174009
Screening for serious mental illness in the general population.
Kessler RC, Barker PR, Colpe LJ, Epstein JF, Gfroerer JC, Hiripi E, Howes MJ, Normand SL, Manderscheid RW, Walters EE, Zaslavsky AM
Arch Gen Psychiatry 2003 Feb;60(2):184-9. doi: 10.1001/archpsyc.60.2.184. PMID: 12578436
The AUDIT alcohol consumption questions (AUDIT-C): an effective brief screening test for problem drinking. Ambulatory Care Quality Improvement Project (ACQUIP). Alcohol Use Disorders Identification Test.
Bush K, Kivlahan DR, McDonell MB, Fihn SD, Bradley KA
Arch Intern Med 1998 Sep 14;158(16):1789-95. doi: 10.1001/archinte.158.16.1789. PMID: 9738608

Recent systematic reviews

Risk Factors for Gambling Disorder: A Systematic Review.
Moreira D, Azeredo A, Dias P
J Gambl Stud 2023 Jun;39(2):483-511. Epub 2023 Mar 8 doi: 10.1007/s10899-023-10195-1. PMID: 36884150Free PMC Article
Supervised Injection Facilities as Harm Reduction: A Systematic Review.
Levengood TW, Yoon GH, Davoust MJ, Ogden SN, Marshall BDL, Cahill SR, Bazzi AR
Am J Prev Med 2021 Nov;61(5):738-749. Epub 2021 Jul 1 doi: 10.1016/j.amepre.2021.04.017. PMID: 34218964Free PMC Article
Motivational interviewing for substance abuse.
Smedslund G, Berg RC, Hammerstrøm KT, Steiro A, Leiknes KA, Dahl HM, Karlsen K
Cochrane Database Syst Rev 2011 May 11;2011(5):CD008063. doi: 10.1002/14651858.CD008063.pub2. PMID: 21563163Free PMC Article
Schizophrenia and violence: systematic review and meta-analysis.
Fazel S, Gulati G, Linsell L, Geddes JR, Grann M
PLoS Med 2009 Aug;6(8):e1000120. Epub 2009 Aug 11 doi: 10.1371/journal.pmed.1000120. PMID: 19668362Free PMC Article
Research on religion, spirituality, and mental health: a review.
Koenig HG
Can J Psychiatry 2009 May;54(5):283-91. doi: 10.1177/070674370905400502. PMID: 19497160

Supplemental Content

Table of contents

    Genetic Testing Registry

    Clinical resources

    Practice guidelines

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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2020
      UK NICE Clinical Guideline CG192, Antenatal and postnatal mental health: clinical management and service guidance, 2020

    Consumer resources

    Reviews

    Related information

    • GTR
      Related information in GTR
    • GTR(Clinical)
      Clinical tests in GTR
    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

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